Pharmacokinetic and technical comparison of Sandostatin® LAR® and other formulations of long-acting octreotide

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Title

Pharmacokinetic and technical comparison of Sandostatin® LAR® and other formulations of long-acting octreotide

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Directory of Open Access Journals

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Directory of Open Access Journals

Description

Abstract Background Sandostatin® LAR® (Novartis Pharma AG) is a long-acting repeatable formulation of the somatostatin analogue octreotide, the safety and efficacy of which has been established through 15 years of clinical experience. Recently, other formulations of octreotide using polymer poly(lactic-co-glycolic acid) technology have been developed. This study compares the composition and pharmacokinetic (PK) profile of Sandostatin LAR with three other versions of the depot delivery system ...

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Format

Research paper

Date created

2011-09-01

Creator

Bizec Jean-Claude / Petersen Holger / Schuetz Helmut / Delporte Marie-Laure

Contributing partner

BMC Research Notes

URL

http://www.biomedcentral.com/1756-0500/4/344

Related subjects

Medicine / Biology (General)

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