Mechanisms whereby propofol mediates peripheral vasodilation in humans: sympathoinhibition or direct vascular relaxation?

About this item

Title

Mechanisms whereby propofol mediates peripheral vasodilation in humans: sympathoinhibition or direct vascular relaxation?

Content partner

Victoria University of Wellington

Collection

Open Access Victoria University of Wellington

Description

Background: Anesthetic induction and maintenance with propofol are associated with decreased blood pressure that is, in part, due to decreased peripheral resistance. Several possible mechanisms whereby propofol could reduce peripheral resistance include a direct action of propofol on vascular smooth muscle, an inhibition of sympathetic activity to the vasculature, or both. This study examined these two possibilities in humans by measuring the forearm vascular responses to infusions of propofo...

Read more

Format

Research paper

Research format

Scholarly text / Journal article

Date created

1997

Creator

Brian Robinson / TJ Ebert / TJ O'Brien / MD Colinco / M Muzi

URL

https://figshare.com/articles/journal_contribution/Mechanisms_whereby_propofol_mediates_periphera...

Related subjects

Biomedical and clinical sciences / Cardiovascular medicine and haematology / Clinical sciences / anesthetics, intravenous, propofol / measurement techniques, plethysmography, forearm blood flow / Cardiorespiratory Medicine and Haematology / Clinical / Clinical Medicine and Science / Clinical Research / Neurosciences / Cardiovascular / Adult / Anesthetics, Intravenous / Brachial Artery / Female / Forearm / Humans / Male / Propofol / Stellate Ganglion / Sympathetic Nervous System / Vascular Resistance / Vasodilation / Vasodilator Agents / Biomedical and Clinical Sciences / Clinical Sciences / Anesthesiology

What is the copyright status of this item?

Share

See below for specifics about how you may use this item.

More Information

Victoria University of Wellington has this to say about the rights status of this item:

CC BY-NC-ND 4.0

What can I do with this item?

You must always check with Victoria University of Wellington to confirm the specific terms of use, but this is our understanding:

Non-infringing use

NZ Copyright law does not prevent every use of a copyright work. You should consider what you can and cannot do with a copyright work.

Share it

This item is suitable for copying and sharing with others, without further permission.

No modifying

You are not allowed to adapt or remix this item into any other works.

No commercial use

You may not use this item commercially.