Design and clinical pilot testing of the model-based Dynamic Insulin Sensitivity and Secretion Test (DISST)

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Title

Design and clinical pilot testing of the model-based Dynamic Insulin Sensitivity and Secretion Test (DISST)

Content partner

University of Canterbury Library

Collection

UC Research Repository

Description

Background: Insulin resistance is a significant risk factor in the pathogenesis of type 2 diabetes. This article presents pilot study results of the dynamic insulin sensitivity and secretion test (DISST), a high-resolution, low-intensity test to diagnose insulin sensitivity (IS) and characterize pancreatic insulin secretion in response to a (small) glucose challenge. This pilot study examines the effect of glucose and insulin dose on the DISST, and tests its repeatability. Methods: DISST test...

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Format

Research paper

Research format

Journal article

Date created

2010

URL

http://hdl.handle.net/10092/5281

Related subjects

insulin resistance / insulin sensitivity / type 2 diabetes diagnosis / physiological modeling / pilot study / Biomedical and clinical sciences / Cardiovascular medicine and haematology / Haematology / Clinical sciences / Endocrinology / Medical and Health Sciences / Medical Biochemistry and Metabolomics / Mathematical Sciences

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