A method for assessment of blood volume parameters in pregnant sheep using fluorescein-labelled dextran

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Title

A method for assessment of blood volume parameters in pregnant sheep using fluorescein-labelled dextran

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

The assessment of blood volume parameters in clinical and research settings has been limited by methods that involve radioactivity, complex assays or are unreliable. We aimed to design a method for measuring blood volume parameters that was non-radioactive, simple, cheap and reliable. We have used a commercially available fluorescein-labelled 250 kDa dextran, a large inert molecule, and have measured dilution of this through the intravascular space of pregnant ewes. From this estimation of pl...

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Format

Research paper

Research format

Journal article

Date created

2008-01

Creator

Rumball, Christopher / Van Zijl, P / Rutland, MD / Bloomfield, Francis / Harding, Jane

URL

http://hdl.handle.net/2292/6309

Related subjects

plasma volume / red cell volume / radiolabelled red cells / pregnancy / ovine / PLASMA-VOLUME / RED-CELL / RESPONSES / RATS

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