Double sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle.

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Title

Double sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

We present a curve-fitting approach that permits quantitative comparisons of fatigue profiles obtained with different stimulation protocols in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of mice. Profiles from our usual stimulation protocol (125 Hz for 500 ms, evoked once every second for 100–300 s) could be fitted by single-term functions (sigmoids or exponentials) but not by a double exponential. A clearly superior fit, as confirmed by the Akaiki Info...

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Format

Research paper

Research format

Journal article

Date created

2008

Creator

Cairns, Simeon / Robinson, Dean / Loiselle, Denis

URL

http://hdl.handle.net/2292/7793

Related subjects

MAMMALIAN SKELETAL-MUSCLE / INORGANIC-PHOSPHATE / FORCE DECLINE / TETANIC FORCE / SOLEUS MUSCLE / RAT HINDLIMB / MOTOR UNITS / P-I / STIMULATION / FIBERS

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