The distribution of the growth factors FGF-2 and VEGF, and their receptors, in growing red deer antler

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Title

The distribution of the growth factors FGF-2 and VEGF, and their receptors, in growing red deer antler

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

The cellular distributions of the growth factors FGF-2 and VEGF, and their receptors FGFR1, FGFR2 and FGFR3, and VEGFR-2 respectively, were visualized by immunohistochemistry and light microscopy in sections of growing red deer antler. Both of these signalling systems were widely expressed in the integument and osteocartilaginous compartments. FGF-2 was found in the same cells as all three FGFRs, indicating that FGF signalling may be principally autocrine. The patterns of labelling for VEGF a...

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Format

Research paper

Research format

Journal article

Date created

2007

Creator

Lai, AK / Hou, Weilin / Verdon, Daniel / Nicholson, Louise / Barling, Peter

URL

http://hdl.handle.net/2292/9200

Related subjects

FGF-2 / FGFR1 / FGFR2 / FGFR3 / VEGF / VEGFR-2 / antler / integument / epidermis / mesenchyme / chondrocyte / osteoblast / immunohistochemistry / BONE-GROWTH / OSTEOBLAST DIFFERENTIATION / FACTOR EXPRESSION / FIBROBLAST / ANGIOGENESIS / SURVIVAL / MICE / INDUCTION / SKIN

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