Gene-expression profiling during curcumin-induced apoptosis reveals downregulation of CXCR4.

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Title

Gene-expression profiling during curcumin-induced apoptosis reveals downregulation of CXCR4.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

A dietary compound curcumin hardwires to multiple cellular processes, with suppression of cell proliferation, induction of apoptosis, and inhibition of metastasis considered as the major mechanisms underlying its anticancer properties. Based on our recent evidence that curcumin triggers cell demise in follicular lymphoma (FL) cells, we aimed to identify curcumin-regulated genes of utmost importance for the treatment of follicular lymphoma.

Format

Research paper

Research format

Journal article

Date created

2007-01

Creator

Skommer, Joanna / Wlodkowic, Donald / Pelkonen, J

URL

http://hdl.handle.net/2292/9704

Related subjects

Antigens, CD20 / Apoptosis / Cell Line, Tumor / Curcumin / Down-Regulation / Gene Expression Profiling / Gene Expression Regulation, Neoplastic / Humans / Lymphoma, Follicular / Receptors, CXCR4

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