Cytotoxicity of the small molecule Bcl-2 antagonist, HA14-1, and selected anticancer drugs in follicular lymphoma B-cells.

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Title

Cytotoxicity of the small molecule Bcl-2 antagonist, HA14-1, and selected anticancer drugs in follicular lymphoma B-cells.

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The University of Auckland Library

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ResearchSpace@Auckland

Description

The Bcl-2 overexpression is a hallmark of follicular lymphoma (FL). Since patients with FL often suffer from progressively resistant to chemotherapy refractory disease, the development of new regiments is required. In this study we analyzed for the first time the effects of a Bcl-2 antagonist, HA14-1, alone and in combination with antineoplastic agents commonly used against follicular lymphoma, in human FL cell lines with t(14;18). The cell lines were established from patient samples send for...

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Format

Research paper

Research format

Conference item

Date created

2005

Creator

Wlodkowic, Donald / Skommer, JS / Matto, M / Eray, ME / Pelkonen, J

URL

http://hdl.handle.net/2292/9741

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