Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: Implications for therapeutics

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Title

Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: Implications for therapeutics

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Cannabinoid Receptor 1 (CB1), an abundant G-protein coupled receptor in the CNS, is currently of significant interest as a therapeutic target. Although the cellular control of receptor trafficking is intimately linked with drug effects, CB1 trafficking is poorly defined in the current literature and conflicting evidence exists as to whether CB1 should be classified as a recycling, degrading or “dual-fate” receptor. Of particular interest is the widely noted intracellular pool which has been s...

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Format

Research paper

Research format

Journal article

Date created

2010-10

Creator

Grimsey, Natasha / Graham, Euan / Dragunow, Michael / Glass, Michelle

URL

http://hdl.handle.net/2292/10466

Related subjects

Animals / Cannabinoids / Cell Line / Cell Membrane / Cricetinae / Cytoplasm / Humans / Protein Transport / Rats / Receptors, Cannabinoid / Receptors, G-Protein-Coupled

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