Metabolic interactions with piperazine-based 'party pill' drugs

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Title

Metabolic interactions with piperazine-based 'party pill' drugs

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Objectives Tarty pills' have found use worldwide its a substitute for amphetamine-derived designer drugs. Whilst some information exists about the metabolism of these drugs, there is little information about their ability to inhibit the metabolism of co-administered drugs. This study aimed to determine whether predictions call be made about. A interactions between 'party pills' Constituents and other drugs metabolised by the same cytochrome P450 (CYP) isoenzymes.Methods The inhibitory effects...

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Format

Research paper

Research format

Journal article

Date created

2009-07

Creator

Antia, Ushtana / Tingle, Malcolm / Russell, Bruce

URL

http://hdl.handle.net/2292/11629

Related subjects

cytochrome P450 isoenzymes / benzylpiperazine / drug-drug interactions / trifluoromethylphenylpiperazine / piperazine analogues / HUMAN LIVER-MICROSOMES / RAT-BRAIN / IN-VIVO / PHARMACOKINETICS / IDENTIFICATION / MECHANISM / ECSTASY / ANALOGS / HUMANS / TFMPP

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