Age-dependent values of N-terminal pro-B-type natriuretic peptide are superior to a single cut-point for ruling out suspected systolic dysfunction in primary care

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Title

Age-dependent values of N-terminal pro-B-type natriuretic peptide are superior to a single cut-point for ruling out suspected systolic dysfunction in primary care

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

The study evaluated the use of age-related decision limits for N-terminal pro-B-type natriuretic peptide (NT-proBNP), for ruling out suspected systolic dysfunction in symptomatic patients in primary care, compared with the present standards.Data were obtained from 5508 patients from 10 studies in the UK, New Zealand, Europe, and USA. All have had NT-proBNP analysis and echocardiography. The median age was 62 years (range 18-100 years) with a prevalence of reduced left ventricular systolic fun...

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Format

Research paper

Research format

Journal article

Date created

2010-08-01

Creator

Hildebrandt, P / Collinson, PO / Doughty, Robert / Fuat, A / Gaze, DC / Gustafsson, F / Januzzi, J / Rosenberg, J / Senior, R / Richards, M

URL

http://hdl.handle.net/2292/15334

Related subjects

Science & Technology / Life Sciences & Biomedicine / Cardiac & Cardiovascular Systems / Cardiovascular System & Cardiology / Natriuretic peptides / Chronic heart failure / Diagnosis / Decision limits / HEART-FAILURE / PRIMARY-CARE / DIAGNOSTIC-ACCURACY / METAANALYSIS / POPULATION / PROGNOSIS / STATEMENT / COMMUNITY / SURVIVAL / MARKER

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