CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients

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Title

CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

1. The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer. The present study investigated associations between survival in acute coronary syndromes (ACS), smoking and the CYP1A1 T6235C polymorphism.2. Patients with ACS (n = 1251) were genotyped for the CYP1A1 T6235C polymorphism. Patients had a mean age of 67.0 years, 69.8% were male and follow up occurred over a median of 1.9 years.3....

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Format

Research paper

Research format

Journal article

Date created

2010-02-01

Creator

Jarvis, MD / Palmer, BR / Pilbrow, AP / Ellis, KL / Frampton, CM / Skelton, L / Doughty, Robert / Whalley, Gillian / Ellis, CJ / Yandle, TG / Richards, AM / Cameron, VA

URL

http://hdl.handle.net/2292/15342

Related subjects

Science & Technology / Life Sciences & Biomedicine / Pharmacology & Pharmacy / Physiology / coronary artery disease / CYP1A1 / gene-environment interaction / genetics / smoking / LUNG-CANCER / NATRIURETIC PEPTIDE / MSPI POLYMORPHISM / ARTERY DISEASE / ATHEROSCLEROSIS / SUSCEPTIBILITY / SMOKING / RISK

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