Genetic adult lactase persistence is associated with risk of Crohn's Disease in a New Zealand population

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Title

Genetic adult lactase persistence is associated with risk of Crohn's Disease in a New Zealand population

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Directory of Open Access Journals

Description

Abstract Background Mycobacterium avium subspecies paratuberculosis (MAP) is an infective agent found in ruminants and milk products, which has been suggested to increase the risk of gastrointestinal inflammation in genetically susceptible hosts. It is hypothesized that lactase persistence facilitates exposure to such milk products increasing the likelihood of adverse outcomes. Individuals either homozygous or heterozygous for the T allele of DNA variant, rs4988235, located 14kb upstream from...

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Format

Research paper

Date created

2010-12-01

Creator

Morgan Angharad R / Lam Wen / Han Dug / Nolan Deborah J / Fraser Alan G / Tapsell Linda C / Ferguson Lynnette R

Contributing partner

BMC Research Notes

URL

http://www.biomedcentral.com/1756-0500/3/339

Related subjects

Medicine / Biology (General)

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