Azithromycin for Indigenous children with bronchiectasis: study protocol for a multi-centre randomized controlled trial

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Title

Azithromycin for Indigenous children with bronchiectasis: study protocol for a multi-centre randomized controlled trial

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Directory of Open Access Journals

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Directory of Open Access Journals

Description

Abstract Background The prevalence of chronic suppurative lung disease (CSLD) and bronchiectasis unrelated to cystic fibrosis (CF) among Indigenous children in Australia, New Zealand and Alaska is very high. Antibiotics are a major component of treatment and are used both on a short or long-term basis. One aim of long-term or maintenance antibiotics is to reduce the frequency of acute pulmonary exacerbations and symptoms. However, there are few studies investigating the efficacy of long-term ...

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Format

Research paper

Date created

2012-08-01

Creator

Valery Patricia C / Morris Peter S / Grimwood Keith / Torzillo Paul J / Byrnes Catherine A / Masters I / Bauert Paul A / McCallum Gabrielle B / Mobberly Charmaine / Chang Anne B

Contributing partner

BMC Pediatrics

URL

http://www.biomedcentral.com/1471-2431/12/122

Related subjects

Azithromycin / Bronchiectasis / Child / Chronic suppurative lung disease / Indigenous health / Placebo / Pulmonary exacerbation / Randomised controlled trial / Antibiotic resistance / Pediatrics

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