Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial

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Title

Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial

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Directory of Open Access Journals

Description

Abstract Background Cerebral metastases are a common cause of death in patients with melanoma. Systemic drug treatment of these metastases is rarely effective, and where possible surgical resection and/or stereotactic radiosurgery (SRS) are the preferred treatment options. Treatment with adjuvant whole brain radiotherapy (WBRT) following neurosurgery and/or SRS is controversial. Proponents of WBRT report prolongation of intracranial control with reduced neurological events and better palliati...

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Format

Research paper

Date created

2011-04-01

Creator

Forder Peta M / Mandel Catherine / Nowak Anna K / Vardy Janette / Morton Rachael L / Fogarty Gerald / Hong Angela / Hruby George / Burmeister Bryan / Shivalingam Brindha / Dhillon Haryana / Thompson John F

Contributing partner

BMC Cancer

URL

http://www.biomedcentral.com/1471-2407/11/142

Related subjects

Neoplasms / Tumors / Oncology / Including cancer and carcinogens

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