Rabbit model of uncontrolled hemorrhagic shock and hypotensive resuscitation

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Title

Rabbit model of uncontrolled hemorrhagic shock and hypotensive resuscitation

Content partner

Directory of Open Access Journals

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Directory of Open Access Journals

Description

Clinically relevant animal models capable of simulating traumatic hemorrhagic shock are needed. We developed a hemorrhagic shock model with male New Zealand rabbits (2200-2800 g, 60-70 days old) that simulates the pre-hospital and acute care of a penetrating trauma victim in an urban scenario using current resuscitation strategies. A laparotomy was performed to reproduce tissue trauma and an aortic injury was created using a standardized single puncture to the left side of the infrarenal aort...

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Format

Research paper

Date created

2010-12-01

Creator

J.B. Rezende-Neto / S.B. Rizoli / M.V. Andrade / T.A. Lisboa / J.R. Cunha-Melo

Contributing partner

Brazilian Journal of Medical and Biological Research

URL

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001200003

Related subjects

Hemorrhagic shock / Animal model / Resuscitation / Medicine (General) / Biology (General)

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