A randomized phase II study of carboplatin plus pegylated liposomal doxorubicin versus carboplatin plus paclitaxel in platinum sensitive ovarian cancer patients: a Hellenic Cooperative Oncology Group study

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Title

A randomized phase II study of carboplatin plus pegylated liposomal doxorubicin versus carboplatin plus paclitaxel in platinum sensitive ovarian cancer patients: a Hellenic Cooperative Oncology Group study

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Directory of Open Access Journals

Description

Abstract Background Platinum-based combinations are the standard second-line treatment for platinum-sensitive ovarian cancer (OC). This randomized phase II study was undertaken in order to compare the combination of carboplatin and pegylated liposomal doxorubicin (LD) with carboplatin and paclitaxel (CP) in this setting. Methods Patients with histologically confirmed recurrent OC, at the time of or more than 6 months after platinum-based chemotherapy, were randomized to six cycles of CP (carb...

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Format

Research paper

Date created

2010-01-01

Creator

Briasoulis Evangelos / Samantas Epaminondas / Makatsoris Thomas / Timotheadou Eleni / Kosmidis Paris / Kalofonos Haralabos P / Fountzilas George / Bamias Aristotelis / Papadimitriou Christos / Aravantinos Gerasimos / Linardou Helena / Bafaloukos Dimitrios / Christodoulou Christos / Papakostas Pavlos / Pectasides Dimitrios / Dimopoulos Athanasios M

Contributing partner

BMC Medicine

URL

http://www.biomedcentral.com/1741-7015/8/3

Related subjects

Medicine

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