The Women's international study of long-duration oestrogen after menopause (WISDOM): a randomised controlled trial

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Title

The Women's international study of long-duration oestrogen after menopause (WISDOM): a randomised controlled trial

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Directory of Open Access Journals

Description

Abstract Background At the time of feasibility work and final design of the trial there was no randomised control trial evidence for the long-term risks and benefits of hormone replacement therapy. Observational studies had suggested that long term use of estrogen was likely to be associated, amongst other things, with reduced risks of osteoporosis and ischaemic heart disease and increased risks of breast and endometrial cancer. Concomitant use of progestogens had been shown to protect agains...

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Format

Research paper

Date created

2007-02-01

Creator

Meade Tom W / Martin Jeannett / Vickers Madge R

Contributing partner

BMC Women's Health

URL

http://www.biomedcentral.com/1472-6874/7/2

Related subjects

Gynecology and obstetrics / Public aspects of medicine

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