Expression of HPV-11 L1 protein in transgenic Arabidopsis thaliana and Nicotiana tabacum

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Title

Expression of HPV-11 L1 protein in transgenic Arabidopsis thaliana and Nicotiana tabacum

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Directory of Open Access Journals

Description

Abstract Background We have investigated the possibility and feasibility of producing the HPV-11 L1 major capsid protein in transgenic Arabidopsis thaliana ecotype Columbia and Nicotiana tabacum cv. Xanthi as potential sources for an inexpensive subunit vaccine. Results Transformation of plants was only achieved with the HPV-11 L1 gene with the C-terminal nuclear localization signal (NLS-) encoding region removed, and not with the full-length gene. The HPV-11 L1 NLS- gene was stably integrate...

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Format

Research paper

Date created

2007-09-01

Creator

Christensen Neil D / Hitzeroth Inga I / Kohl Thomas O / Rybicki Edward P

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BMC Biotechnology

URL

http://www.biomedcentral.com/1472-6750/7/56

Related subjects

Biotechnology

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