Early pregnancy prediction of preeclampsia in nulliparous women, combining clinical risk and biomarkers: the Screening for Pregnancy Endpoints (SCOPE) international cohort study

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Title

Early pregnancy prediction of preeclampsia in nulliparous women, combining clinical risk and biomarkers: the Screening for Pregnancy Endpoints (SCOPE) international cohort study

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

More than half of all cases of preeclampsia occur in healthy first-time pregnant women. Our aim was to develop a method to predict those at risk by combining clinical factors and measurements of biomarkers in women recruited to the Screening for Pregnancy Endpoints (SCOPE) study of low-risk nulliparous women. Forty-seven biomarkers identified on the basis of (1) association with preeclampsia, (2) a biological role in placentation, or (3) a role in cellular mechanisms involved in the pathogene...

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Format

Research paper

Research format

Journal article

Date created

2014-09

Creator

Kenny, LC / Black, MA / Poston, L / Taylor, Rennae / Myers, JE / Baker, Philip / McCowan, Lesley / Simpson, NA / Dekker, GA / Roberts, CT / Rodems, K / Noland, B / Raymundo, M / Walker, JJ / North, RA

URL

http://hdl.handle.net/2292/24005

Related subjects

Humans / Pre-Eclampsia / Ribonuclease, Pancreatic / Pregnancy Proteins / Mass Screening / Models, Statistical / Biological Markers / Cohort Studies / Random Allocation / Predictive Value of Tests / Body Mass Index / Parity / Blood Pressure / Vascular Resistance / Adult / Pregnancy / International Cooperation / Risk Factors / Female

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