Artemisinin-Naphthoquine versus Artemether-Lumefantrine for Uncomplicated Malaria in Papua New Guinean Children: An Open-Label Randomized Trial

About this item

Title

Artemisinin-Naphthoquine versus Artemether-Lumefantrine for Uncomplicated Malaria in Papua New Guinean Children: An Open-Label Randomized Trial

Content partner

FigShare

Collection

FigShare

Description

BackgroundArtemisinin combination therapies (ACTs) with broad efficacy are needed where multiple Plasmodium species are transmitted, especially in children, who bear the brunt of infection in endemic areas. In Papua New Guinea (PNG), artemether-lumefantrine is the first-line treatment for uncomplicated malaria, but it has limited efficacy against P. vivax. Artemisinin-naphthoquine should have greater activity in vivax malaria because the elimination of naphthoquine is slower than that of lume...

Read more

Format

Data

Date created

30 Dec, 2014

Creator

Moses Laman / Brioni R. Moore / John M. Benjamin / Gumul Yadi / Cathy Bona / Jonathan Warrel / Johanna H. Kattenberg / Tamarah Koleala / Laurens Manning / Bernadine Kasian / Leanne J. Robinson / Naomi Sambale / Lina Lorry / Stephan Karl / Wendy A. Davis / Anna Rosanas-Urgell / Ivo Mueller / Peter M. Siba / Inoni Betuela / Timothy M. E. Davis

URL

https://figshare.com/articles/dataset/_Artemisinin_Naphthoquine_versus_Artemether_Lumefantrine_fo...

Related subjects

dose / vivax malaria / New Zealand Clinical Trials Registry ACTRN 12610000913077Please / Papua New Guinean Children / randomized / ci / efficacy / 28 March 2011 / falciparum / acpr / PNG children / Papua New Guinea / 22 April 2013. Parasitologic outcomes / Biological Sciences

What is the copyright status of this item?

Creative Commons

This item appears to be licensed under a Creative Commons (ZERO) 1.0 CC International license.

More Information

FigShare has this to say about the rights status of this item:

http://figshare.com/licensing

You can learn more about the rights status of this item at: http://creativecommons.org/publicdomain/zero/1.0/

What can I do with this item?

You must always check with FigShare to confirm the specific terms of use, but this is our understanding:

Non-infringing use

NZ Copyright law does not prevent every use of a copyright work. You should consider what you can and cannot do with a copyright work.

Share it

This item is suitable for copying and sharing with others, without further permission.

Modify it

This item is suitable for modifying, remixing and building upon, without further permission.

Use it commercially

This item is suitable for commercial use, without further permission.