Effects of Combined Calcium and Vitamin D Supplementation on Insulin Secretion, Insulin Sensitivity and β-Cell Function in Multi-Ethnic Vitamin D-Deficient Adults at Risk for Type 2 Diabetes: A Pilot Randomized, Placebo-Controlled Trial

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Title

Effects of Combined Calcium and Vitamin D Supplementation on Insulin Secretion, Insulin Sensitivity and β-Cell Function in Multi-Ethnic Vitamin D-Deficient Adults at Risk for Type 2 Diabetes: A Pilot Randomized, Placebo-Controlled Trial

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Description

ObjectivesTo examine whether combined vitamin D and calcium supplementation improves insulin sensitivity, insulin secretion, β-cell function, inflammation and metabolic markers.Design6-month randomized, placebo-controlled trial.ParticipantsNinety-five adults with serum 25-hydroxyvitamin D [25(OH)D] ≤55 nmol/L at risk of type 2 diabetes (with prediabetes or an AUSDRISK score ≥15) were randomized. Analyses included participants who completed the baseline and final visits (treatment n = 35; plac...

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Date created

09 Oct, 2014

Creator

Claudia Gagnon / Robin M. Daly / André Carpentier / Zhong X. Lu / Catherine Shore-Lorenti / Ken Sikaris / Sonia Jean / Peter R. Ebeling

URL

https://figshare.com/articles/dataset/Effects_of_Combined_Calcium_and_Vitamin_D_Supplementation_o...

Related subjects

il / Vitamin D / insulin sensitivity / AUSDRISK / Vitamin D Supplementation / type 2 diabetes / oh / ogtt / prediabete / homa / calcium supplementation / vitamin D status / Insulin secretion / age 54 years / function / observed.ConclusionsDaily vitamin D / nmol / ACTRN / Matsuda index x AUC / iu / tnf / 6 months.MeasurementsInsulin sensitivity / Biological Sciences

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