Oral but Not Intravenous Glucose Acutely Decreases Circulating Interleukin-6 Concentrations in Overweight Individuals

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Title

Oral but Not Intravenous Glucose Acutely Decreases Circulating Interleukin-6 Concentrations in Overweight Individuals

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BackgroundPlasma interleukin-6 (IL-6) concentrations decrease acutely 1 h after ingestion of a glucose load or mixed meals and this may be mediated by an anti-inflammatory effect of insulin. The aim of the present study was to compare the effect of higher versus lower insulin levels on plasma IL-6 concentrations following oral compared with intravenous glucose administration in overweight/obese subjects.Methods and FindingsFifteen subjects (12 women and 3 men) with BMI >28 kg/m2 were given an...

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Date created

12 Jun, 2013

Creator

Patrick J. Manning / Wayne H. F. Sutherland / Sheila M. Williams / Sylvia A. de Jong / Gavin P. Hendry

URL

https://figshare.com/articles/dataset/_Oral_but_Not_Intravenous_Glucose_Acutely_Decreases_Circula...

Related subjects

statistics / Biostatistics / Statistical methods / Anatomy and physiology / Endocrine system / Diabetic endocrinology / Immune physiology / cytokines / Clinical research design / Endocrinology / insulin / Endocrine physiology / nutrition / obesity / intravenous / glucose / acutely / decreases / circulating / interleukin-6 / concentrations / overweight / Mathematics / Medicine

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