About this item
- Title
- Adenosine Amine Congener as a Cochlear Rescue Agent
- Content partner
- The University of Auckland Library
- Collection
- ResearchSpace@Auckland
- Description
We have previously shown that adenosine amine congener (ADAC), a selective A1 adenosine receptor agonist, can ameliorate noise- and cisplatin-induced cochlear injury. Here we demonstrate the dose-dependent rescue effects of ADAC on noise-induced cochlear injury in a rat model and establish the time window for treatment. METHODS: ADAC (25-300 μg/kg) was administered intraperitoneally to Wistar rats (8-10 weeks old) at intervals (6-72 hours) after exposure to traumatic noise (8-16 kHz, 110 dB s...
- Format
- Research paper
- Research format
- Journal article
- Date created
- 2014
- Creator
- Vlajkovic, Srdjan / Chang, H / Paek, SY / Chi, HH-T / Sreebhavan, S / Telang, Ravindra / Tingle, Malcolm / Housley, GD / Thorne, Peter
- URL
- https://hdl.handle.net/2292/24827
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Report this itemDigitalNZ brings together more than 30 million items from institutions so that they are easy to find and use. This information is the best information we could find on this item. This item was added on 12 March 2015, and updated 26 October 2025.
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