Elucidating the Origin of Tetrodotoxin in Pleurobranchaea maculata and Stylochoplana sp.

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Title

Elucidating the Origin of Tetrodotoxin in Pleurobranchaea maculata and Stylochoplana sp.

Content partner

University of Waikato

Collection

ResearchCommons@Waikato

Description

Tetrodotoxin (TTX) is an extremely potent neurotoxin that acts by selectively targeting voltage gated sodium channels blocking propagation of action potentials. Long believed to be present only in pufferfish, TTX has now been detected in a wide range of phylogenetically unrelated terrestrial and aquatic taxa. Despite decades of research the exact origin of TTX remains a mystery. Current literature supports three hypotheses: endogenous, symbiotic bacteria, or bioaccumulation through a dietary ...

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Format

Research Paper

Research format

Thesis

Thesis level

Doctoral

Date created

2015

Creator

Salvitti, Lauren R.

URL

https://hdl.handle.net/10289/9247

Related subjects

tetrodotoxin / Pleurobranchaea maculata / stylochoplana / Opisthobranch / Platyhelminthes / New Zealand / marine ecology / molecular / Tauranga / TTX / immunohistochemistry

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