Pre-Pubertal Children Born Post-Term Have Reduced Insulin Sensitivity and Other Markers of the Metabolic Syndrome

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Title

Pre-Pubertal Children Born Post-Term Have Reduced Insulin Sensitivity and Other Markers of the Metabolic Syndrome

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BackgroundThere are no data on the metabolic consequences of post-term birth (≥42 weeks gestation). We hypothesized that post-term birth would adversely affect insulin sensitivity, as well as other metabolic parameters and body composition in childhood. Methods77 healthy pre-pubertal children, born appropriate-for-gestational-age were studied in Auckland, New Zealand: 36 born post-term (18 boys) and 41 (27 boys) born at term (38–40 weeks gestation). Primary outcome was insulin sensitivity mea...

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Date created

01 Jul, 2013

Creator

Ahila Ayyavoo / José G. B. Derraik / Paul L. Hofman / Sarah Mathai / Janene Biggs / Peter Stone / Lynn Sadler / Wayne S. Cutfield

URL

https://doi.org/10.1371/journal.pone.0067966

Related subjects

children / post-term / reduced / insulin / markers / metabolic / Information and Computing Sciences / Biological Sciences

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