Beta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral artery.

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Title

Beta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral artery.

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Directory of Open Access Journals

Description

BACKGROUND AND PURPOSE: Beta adrenergic overstimulation may increase the vascular damage and stroke. However, the underlying mechanisms of beta adrenergic overstimulation in cerebrovascular dysfunctions are not well known. We investigated the possible cerebrovascular dysfunction response to isoproterenol induced beta-adrenergic overstimulation (ISO) in rabbit cerebral arteries (CAs). METHODS: ISO was induced in six weeks aged male New Zealand white rabbit (0.8-1.0 kg) by 7-days isoproterenol ...

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Research paper

Creator

Hyoung Kyu Kim / Won Sun Park / Mohamad Warda / So Youn Park / Eun A Ko / Min Hee Kim / Seung Hun Jeong / Hye-Jin Heo / Tae-Hoon Choi / Young-Won Hwang / Sun-Il Lee / Kyung Soo Ko / Byoung Doo Rhee / Nari Kim / Jin Han

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PLoS ONE

URL

http://europepmc.org/articles/PMC3423383?pdf=render

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Medicine / Science

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