Ascorbic acid is essential for significant collagen deposition by human tenocytes in vitro

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Title

Ascorbic acid is essential for significant collagen deposition by human tenocytes in vitro

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The University of Auckland Library

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ResearchSpace@Auckland

Description

Objective: We sought to compare L-ascorbic acid (AA), the natural form of vitamin C, and magnesium ascorbyl phosphate (MAP), a stable derivative, for their effect on cell proliferation, culture collagen content and collagen expression in tendon-derived cells. Methods: Tenocytes received these two ascorbate formulations at concentrations between 0.01 mM and 2 M. The effect of supplementation was evaluated in terms of cell growth, collagen expression, collagen secretion, cell morphology and col...

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Format

Research paper

Research format

Journal article

Date created

2014

Creator

Hakimi, O / Poulsen, Raewyn / Thakkar, D / Yapp, C / Carr, A

URL

https://hdl.handle.net/2292/29259

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