Research paper

The effect of Tamoxifen and Fulvestrant on pro-inflammatory markers in oestrogen receptor positive breast cancer

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Title
The effect of Tamoxifen and Fulvestrant on pro-inflammatory markers in oestrogen receptor positive breast cancer
Content partner
University of Otago
Collection
Otago University Research Archive
Description

Oestrogen receptor α (ERα) positive breast cancer is the most prevalent form of breast cancer diagnosed. While a number of therapeutics have been developed targeting the dependence of these cancers on oestrogen for the transcription of genes related to cell growth and proliferation, a significant problem in the treatment of ERα+ breast cancers is the development of oestrogen independent growth. An association between poor antiproliferative response to aromatase inhibitors and an increased lev...

Format
Research paper
Research format
Scholarly text / Thesis
Thesis level
Masters
Date created
2016
Creator
Bundock, Anna
URL
https://hdl.handle.net/10523/6778
Related subjects
Tamoxifen / Fulvestrant / Oestrogen receptor / Breast cancer / Pro-inflammatory / Chemokines / Immune / Oestrogen independent growth / Resistance / Pro-tumour microenvironment / CCL5 / CCL22 / CXCL16 / Oestrogen deprived / MCF-7 / T47D / anti-oestrogen therapy / aromatase inhibitor / in vitro / in vivo / Letrozole / Celecoxib / STAT1-/-

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