Genetic markers of repolarization and arrhythmic events after acute coronary syndromes

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Title

Genetic markers of repolarization and arrhythmic events after acute coronary syndromes

Content partner

The University of Auckland Library

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ResearchSpace@Auckland

Description

BACKGROUND: There is a genetic contribution to the risk of ventricular arrhythmias in survivors of acute coronary syndromes (ACS). We wished to explore the role of 33 candidate single nucleotide polymorphisms (SNPs) in prolonged repolarization and sudden death in patients surviving ACS. METHODS: A total of 2,139 patients (1680 white ethnicity) surviving an admission for ACS were enrolled in the prospective Coronary Disease Cohort Study. Extensive clinical, echocardiographic, and neurohormonal...

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Format

Research paper

Research format

Journal article

Date created

2015-04

Creator

Earle, Nicola / Poppe, Katrina / Pilbrow, AP / Cameron, VA / Troughton, RW / Skinner, Jonathan / Love, Donald / Shelling, Andrew / Whalley, Gillian / Ellis, CJ / Richards, AM / Doughty, Robert

URL

http://hdl.handle.net/2292/30447

Related subjects

Humans / Genetic Predisposition to Disease / DNA / Genetic Markers / Electrocardiography / Risk Factors / Follow-Up Studies / Prospective Studies / Genotype / Polymorphism, Single Nucleotide / Aged / Female / Male / Arrhythmias, Cardiac / Acute Coronary Syndrome

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