Effects of periconceptional undernutrition on the initiation of parturition in sheep

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Title

Effects of periconceptional undernutrition on the initiation of parturition in sheep

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

In sheep, parturition is initiated by increased fetal hypothalamic-pituitary-adrenal axis ( HPAA) activity leading to PGE(2) and PGF(2alpha) production and a rise in the 17beta-estradiol-progesterone (E-2/P-4) ratio. Uteroplacental PG production can also increase fetal HPAA activity. Periconceptional maternal undernutrition accelerates fetal HPAA maturation resulting in preterm labor. We determined whether preterm labor was preceded by an increase in PG concentrations and E-2/P-4 ratio and wh...

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Format

Research paper

Research format

Journal article

Date created

2005-01

Creator

Kumarasamy, Vasumathy / Mitchell, Murray / Bloomfield, Francis / Oliver, Mark / Campbell, ME / Challis, JRG / Harding, Jane

URL

http://hdl.handle.net/2292/31149

Related subjects

hypothalamic-pituitary-adrenal axis / prostaglandin / cortisol / estrogen-progesterone ratio / PITUITARY-ADRENAL-FUNCTION / LATE-GESTATION / FETAL SHEEP / PROSTAGLANDIN PRODUCTION / LATE PREGNANCY / PLASMA / LABOR / ADRENOCORTICOTROPIN / INHIBITION / TERM

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