Generalisability of a virtual trials method for glycaemic control in intensive care

About this item

Title

Generalisability of a virtual trials method for glycaemic control in intensive care

Content partner

University of Canterbury Library

Collection

UC Research Repository

Description

Elevated blood glucose (BG) concentrations (Hyperglycaemia) are a common complication in critically ill patients. Insulin therapy is commonly used to treat hyperglycaemia, but metabolic variability often results in poor BG control and low BG (hypoglycaemia).This paper presents a model-based virtual trial method for glycaemic control protocol design, and evaluates its generalisability across different populations.Model-based insulin sensitivity (SI) was used to create virtual patients from cli...

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Format

Research paper

Research format

Journal article

Date created

2017

Creator

Dickson JL / Stewart KW / Pretty CG / Flechet M / Desaive T / Penning S / Lambermont BC / Benyo B / Shaw, Geoff / Chase, Geoff

URL

http://hdl.handle.net/10092/13551

Related subjects

Glycaemic control / virtual trials / insulin sensitivity / Biomedical and clinical sciences / Clinical sciences / Endocrinology / Intensive care

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