Interstitial insulin kinetic parameters for a 2-compartment insulin model with saturable clearance

About this item

Title

Interstitial insulin kinetic parameters for a 2-compartment insulin model with saturable clearance

Content partner

University of Canterbury Library

Collection

UC Research Repository

Description

Glucose-insulin system models are commonly used for identifying insulin sensitivity. With physiological, 2-compartment insulin kinetics models, accurate kinetic parameter values are required for reliable estimates of insulin sensitivity. This study uses data from 6 published microdialysis studies to determine the most appropriate parameter values for the transcapillary diffusion rate (nI) and cellular insulin clearance rate (nC).The 6 studies (12 data sets) used microdialysis techniques to si...

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Format

Research paper

Research format

Journal article

Date created

2014

Creator

Pretty CG / Le Compte A / Penning S / Fisk L / Shaw, Geoff / Desaive T / Chase, Geoff

URL

http://hdl.handle.net/10092/13554

Related subjects

Biomedical system modelling / Simulation and visualisation / Control of physiological and clinical variables / Engineering / Biomedical Engineering / Biomedical and clinical sciences / Clinical sciences / Endocrinology

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