Effect of single-dose dexamethasone on acute phase response following zoledronic acid: a randomized controlled trial

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Title

Effect of single-dose dexamethasone on acute phase response following zoledronic acid: a randomized controlled trial

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Zoledronic acid provokes an inflammatory reaction, or acute phase response, in some individuals. We examined whether treatment with dexamethasone could prevent this response. A single dose of dexamethasone 4 mg, given at the time of zoledronic acid infusion, did not influence the incidence or severity of the acute phase response.The potent bisphosphonate zoledronic acid (ZOL) is used to treat osteoporosis, Paget's disease, and hypercalcemia of malignancy. This medication can provoke an inflam...

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Format

Research paper

Research format

Journal article

Date created

2017-06

Creator

Billington, Emma / Horne, Anne / Gamble, Gregory / Maslowski, K / House, Meaghan / Reid, Ian

URL

https://hdl.handle.net/2292/33466

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