In Vivo Confocal Microscopy of Corneal Nerves: An Ocular Biomarker for Peripheral and Cardiac Autonomic Neuropathy in Type 1 Diabetes Mellitus

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Title

In Vivo Confocal Microscopy of Corneal Nerves: An Ocular Biomarker for Peripheral and Cardiac Autonomic Neuropathy in Type 1 Diabetes Mellitus

Content partner

The University of Auckland Library

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ResearchSpace@Auckland

Description

We investigated the relationship between corneal subbasal nerve (SBN) plexus density, corneal sensitivity, and peripheral and cardiac autonomic neuropathy in patients with type 1 diabetes mellitus.We recruited 53 patients with type 1 diabetes mellitus and 40 normal control participants. Corneal in vivo confocal microscopy (IVCM) and sensitivity testing were performed on one eye of each subject. Autonomic function testing was done and an overall neuropathy score obtained from a combination of ...

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Format

Research paper

Research format

Journal article

Date created

2015-08

Creator

Misra, Stuti / Craig, Jennifer / Patel, Dipika / McGhee, Charles / Pradhan, M / Ellyett, K / Kilfoyle, D / Braatvedt, Geoffrey

URL

http://hdl.handle.net/2292/34913

Related subjects

Autonomic Nervous System / Cornea / Humans / Autonomic Nervous System Diseases / Peripheral Nervous System Diseases / Diabetic Neuropathies / Heart Diseases / Diabetes Mellitus, Type 1 / Microscopy, Confocal / Reproducibility of Results / Adolescent / Adult / Aged / Middle Aged / Female / Male / Young Adult

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