Ultrasound-mediated nanoparticle delivery across ex vivo bovine retina after intravitreal injection

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Title

Ultrasound-mediated nanoparticle delivery across ex vivo bovine retina after intravitreal injection

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Intravitreal injection is the most common administration route for the treatment of retinal diseases. However, the vitreous and some of the retinal layers themselves act as significant barriers to efficient delivery of drugs administered intravitreally. This study aimed to improve the diffusive mobility of nanoparticles (NPs) in the vitreous and enhance their permeation across the retina after intravitreal injection by application of ultrasound (US). Ex vivo posterior bovine eye cups were use...

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Format

Research paper

Research format

Journal article

Date created

2017-10

Creator

Huang, Di / Chen, Ying-Shan / Thakur, Sachin / Rupenthal, Ilva

URL

http://hdl.handle.net/2292/35062

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• http://purl.org/eprint/accessRights/OpenAccess

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