The locus for an inherited cataract in sheep maps to ovine chromosome 6

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Title

The locus for an inherited cataract in sheep maps to ovine chromosome 6

Content partner

Lincoln University

Collection

Lincoln University Research Archive

Description

Purpose: Cataracts are an important cause of blindness in humans but there are few large animal models available. One of these animal models is Ovine Heritable Cataract, a bilateral cortical cataract which develops after birth. This cataract has been used as a model for human cataracts in drug trials, but the gene responsible for the cataract trait is unknown. A genetic test for cataract would improve the efficiency of the model by predicting which animals would develop cataracts. Identifyin...

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Format

Research Paper

Research format

Journal article

Date created

2012-05-31

Creator

Wilson, GRS / Morton, James / Palmer, DN / McEwan, JC / Gately, K / Anderson, RM / Dodds, KG

URL

https://hdl.handle.net/10182/8612

Related subjects

sheep / inherited cataract / ovine chromosome 6 / Ovine Heritable Cataract (OHC) / blindness / Chromosomes, Mammalian / Animals / Cattle / Sheep / Sheep, Domestic / Humans / Cataract / Disease Models, Animal / Sheep Diseases / Pyrophosphatases / DNA-Binding Proteins / Chromosome Mapping / Pedigree / Microsatellite Repeats / Genotype / Phenotype / Polymorphism, Restriction Fragment Length / Polymorphism, Single Nucleotide / Genetic Testing / Genetic Loci / Genetic Linkage / Animal Production / Ophthalmology and optometry

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