SIRFLOX: Randomized phase III trial comparing first-line mFOLFOX6 (plus or minus Bevacizumab) versus mFOLFOX6 (plus or minus Bevacizumab) plus Selective Internal Radiation Therapy in patients with metastatic colorectal cancer

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Title

SIRFLOX: Randomized phase III trial comparing first-line mFOLFOX6 (plus or minus Bevacizumab) versus mFOLFOX6 (plus or minus Bevacizumab) plus Selective Internal Radiation Therapy in patients with metastatic colorectal cancer

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

SIRFLOX was a randomized, multicenter trial designed to assess the efficacy and safety of adding selective internal radiation therapy (SIRT) using yttrium-90 resin microspheres to standard fluorouracil, leucovorin, and oxaliplatin (FOLFOX)-based chemotherapy in patients with previously untreated metastatic colorectal cancer. Chemotherapy-naïve patients with liver metastases plus or minus limited extrahepatic metastases were randomly assigned to receive either modified FOLFOX (mFOLFOX6; contro...

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Format

Research paper

Research format

Journal article

Date created

2016-05

Creator

van Hazel, GA / Heinemann, V / Sharma, NK / Findlay, Michael / Ricke, J / Peeters, M / Perez, D / Robinson, BA / Strickland, AH / Ferguson, T / Rodríguez, J / Kröning, H / Wolf, I / Ganju, V / Walpole, E / Boucher, E / Tichler, T / Shacham-Shmueli, E / Powell, A / Eliadis, P / Isaacs, R / Price, D / Moeslein, F / Taieb, J / Bower, G / Gebski, V / Van Buskirk, M / Cade, DN / Thurston, K / Gibbs, P

URL

http://hdl.handle.net/2292/35911

Related subjects

Humans / Colorectal Neoplasms / Neoplasm Metastasis / Organoplatinum Compounds / Fluorouracil / Leucovorin / Antineoplastic Combined Chemotherapy Protocols / Combined Modality Therapy / Brachytherapy / Adult / Aged / Aged, 80 and over / Middle Aged / Female / Male

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