Maternal high fat diet alters skeletal muscle mitochondrial catalytic activity in adult male rat offspring

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Title

Maternal high fat diet alters skeletal muscle mitochondrial catalytic activity in adult male rat offspring

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

A maternal high-fat (HF) diet during pregnancy can lead to metabolic compromise, such as insulin resistance in adult offspring. Skeletal muscle mitochondrial dysfunction is one mechanism contributing to metabolic impairments in insulin resistant states. Therefore, the present study aimed to investigate whether mitochondrial dysfunction is evident in metabolically compromised offspring born to HF-fed dams. Sprague-Dawley dams were randomly assigned to receive a purified control diet (CD; 10% k...

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Format

Research paper

Research format

Journal article

Date created

2016-11

Creator

Pileggi, CA / Hedges, Christopher / Segovia, SA / Markworth, JF / Durainayagam, BR / Gray, C / Zhang, XD / Barnett, Matthew / Vickers, Mark / Hickey, Anthony / Reynolds, Clare / Cameron-Smith, David

URL

http://hdl.handle.net/2292/36108

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• http://purl.org/eprint/accessRights/OpenAccess

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