Using the rd1 mouse to understand functional and anatomical retinal remodelling and treatment implications in retinitis pigmentosa: A review

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Title

Using the rd1 mouse to understand functional and anatomical retinal remodelling and treatment implications in retinitis pigmentosa: A review

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Retinitis Pigmentosa (RP) reflects a range of inherited retinal disorders which involve photoreceptor degeneration and retinal pigmented epithelium dysfunction. Despite the multitude of genetic mutations being associated with the RP phenotype, the clinical and functional manifestations of the disease remain the same: nyctalopia, visual field constriction (tunnel vision), photopsias and pigment proliferation. In this review, we describe the typical clinical phenotype of human RP and review the...

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Format

Research paper

Research format

Journal article

Date created

2016-09

Creator

Kalloniatis, Michael / Nivison-Smith, L / Chua, J / Acosta Etchebarne, Monica / Fletcher, EL

URL

http://hdl.handle.net/2292/36141

Related subjects

Retina / Animals / Mice, Transgenic / Humans / Mice / Retinitis Pigmentosa / Disease Models, Animal / Retinal Pigment Epithelium / Genetic Therapy

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