Research paper

Vinpocetine modulates metabolic activity and function during retinal ischemia

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About this item

Title
Vinpocetine modulates metabolic activity and function during retinal ischemia
Content partner
The University of Auckland Library
Collection
ResearchSpace@Auckland
Description

Vinpocetine protects against a range of degenerative conditions and insults of the central nervous system via multiple modes of action. Little is known, however, of its effects on metabolism. This may be highly relevant, as vinpocetine is highly protective against ischemia, a process that inhibits normal metabolic function. This study uses the ischemic retina as a model to characterize vinpocetine's effects on metabolism. Vinpocetine reduced the metabolic demand of the retina following ex viv...

Format
Research paper
Research format
Journal article
Date created
2015-05
Creator
Nivison-Smith, L / O'Brien, BJ / Truong, M / Guo, Xiaopeng / Kalloniatis, M / Acosta Etchebarne, Monica
URL
http://hdl.handle.net/2292/36724
Related subjects
Animals / Rats, Sprague-Dawley / Retinal Diseases / Ischemia / Disease Models, Animal / Vinca Alkaloids / L-Lactate Dehydrogenase / Glucose / Glutamic Acid / Neuroprotective Agents / Electroretinography / Tissue Culture Techniques / Cell Death / Energy Metabolism / Evoked Potentials / Cytoprotection / Dose-Response Relationship, Drug / Ependymoglial Cells

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