Determination of membrane disruption and genomic DNA binding of cinnamaldehyde to Escherichia coli by use of microbiological and spectroscopic techniques

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Title

Determination of membrane disruption and genomic DNA binding of cinnamaldehyde to Escherichia coli by use of microbiological and spectroscopic techniques

Content partner

Lincoln University

Collection

Lincoln University Research Archive

Description

This work was aimed to investigate the antibacterial action of cinnamaldehyde (CIN) against Escherichia coli ATCC 8735 (E. coli) based on membrane fatty acid composition analysis, alterations of permeability and cell morphology as well as interaction with genomic DNA. Analysis of membrane fatty acids using gas chromatography-mass spectrometry (GC-MS) revealed that the proportion of unsaturated fatty acids (UFA) and saturated fatty acids (SFA) were the major fatty acids in plasmic membrane, an...

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Format

Research Paper

Research format

Journal article

Date created

2018-01

Creator

He, T-F / Zhang, Z-H / Zeng, X-A / Wang, L-H / Brennan, CS

URL

https://hdl.handle.net/10182/10122

Related subjects

cinnamaldehyde / Escherichia coli / membrane fatty acid / genomic DNA / Cell Wall / Acrolein / Fatty Acids / Fatty Acids, Unsaturated / DNA / Anti-Bacterial Agents / Microscopy, Electron, Scanning / Microscopy, Atomic Force / Spectrophotometry, Ultraviolet / Circular Dichroism / Binding Sites / Nucleic Acid Conformation / Gas Chromatography-Mass Spectrometry / Molecular Docking Simulation / Food Sciences / Physical chemistry

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