Comparison of 1% cyclosporine eye drops in olive oil and in linseed oil to treat experimentally-induced keratoconjunctivitis sicca in rabbits

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Comparison of 1% cyclosporine eye drops in olive oil and in linseed oil to treat experimentally-induced keratoconjunctivitis sicca in rabbits

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ABSTRACTPurpose:To evaluate the effectiveness of topical 1% cyclosporine eye drops diluted in either of the two vehicles-olive and linseed oil-and that of the oils themselves in treating experimentally-induced keratoconjunctivitis sicca (KCS) in rabbits.Methods:KCS was induced in 25 New Zealand rabbits using 1% atropine sulfate eye drops for 7 days before treatment and throughout the treatment period (12 weeks). The rabbits were divided into five groups: one control (C) group without KCS indu...

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Date created

19 Sep, 2018

Creator

Leticia Rodrigues Parrilha / Gisele Alborghetti Nai / Rogério Giuffrida / Rafael Cabral Barbero / Leticia Dias Fabris Padovani / Ricardo Henrique Zaquir Pereira / Danielle Alves Silva / Mariele Catherine Alves Silva / Miriely Stein Diniz / Silvia Franco Andrade

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https://figshare.com/articles/dataset/Comparison_of_1_cyclosporine_eye_drops_in_olive_oil_and_in_...

Related subjects

Cyclosporine/administration & dosage / Olive oil / Linseed oil / Keratoconjunctivitis sicca / Rabbits / Ophthalmology

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