The presence of ∆133p53 and ∆40p53 in metastatic brain tumours: evidence for further enquiries

About this item

Title

The presence of ∆133p53 and ∆40p53 in metastatic brain tumours: evidence for further enquiries

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Metastatic brain tumours are becoming more prevalent as individuals with primary cancers receive improved treatment and live longer. These brain tumours are difficult to treat and are often left undiagnosed. This study looked at determining if tumour protein 53 (p53) isoforms were expressed in brain metastases. An isoform investigated, ∆133p53, has been implicated in promoting tumour migration and in primary brain tumours was associated with treatment resistance and inflammatory characteristi...

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Format

Research paper

Research format

Scholarly text / Thesis

Thesis level

Masters

Date created

2018

Creator

Tahmeedzaman, Quazi

URL

https://hdl.handle.net/10523/8604

Related subjects

P53 / P53 Isoforms / Metastatic Brain Cancer / ∆133p53 / ∆40p53 / RNAScope / PDL1

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