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Title

Alzheimer's Disease and Histone Code Alterations.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Substantial progress has been made in identifying Alzheimer's disease (AD) risk-associated variants using genome-wide association studies (GWAS). The majority of these risk variants reside in noncoding regions of the genome making their functional evaluation difficult; however, they also infer the presence of unconventional regulatory regions that may reside at these locations. We know from these studies that rare familial cases of AD account for less than 5% of all AD cases and autosomal dom...

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Format

Research paper

Research format

Book item

Date created

2017-01

Creator

Narayan, Pritika / Dragunow, Michael

URL

http://hdl.handle.net/2292/42957

Related subjects

Animals / Humans / Mice / Alzheimer Disease / Disease Models, Animal / Histone Deacetylases / Histone-Lysine N-Methyltransferase / Nerve Tissue Proteins / Histones / Risk Factors / Epigenesis, Genetic / Protein Processing, Post-Translational / Brain Chemistry / Histone Code / Acetylation / Methylation / Phosphorylation / Mutation / Apolipoprotein E4 / Histone Deacetylase Inhibitors

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