Three-dimensional Integrated Functional, Structural, and Computational Mapping to Define the Structural "Fingerprints" of Heart-Specific Atrial Fibrillation Drivers in Human Heart Ex Vivo.

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Title

Three-dimensional Integrated Functional, Structural, and Computational Mapping to Define the Structural "Fingerprints" of Heart-Specific Atrial Fibrillation Drivers in Human Heart Ex Vivo.

Content partner

The University of Auckland Library

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ResearchSpace@Auckland

Description

Structural remodeling of human atria plays a key role in sustaining atrial fibrillation (AF), but insufficient quantitative analysis of human atrial structure impedes the treatment of AF. We aimed to develop a novel 3-dimensional (3D) structural and computational simulation analysis tool that could reveal the structural contributors to human reentrant AF drivers.High-resolution panoramic epicardial optical mapping of the coronary-perfused explanted intact human atria (63-year-old woman, chron...

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Format

Research paper

Research format

Journal article

Date created

2017-08-22

Creator

Zhao, Jichao / Hansen, Brian J / Wang, Yufeng / Csepe, Thomas A / Sul, Lidiya V / Tang, Alan / Yuan, Yiming / Li, Ning / Bratasz, Anna / Powell, Kimerly A / Kilic, Ahmet / Mohler, Peter J / Janssen, Paul ML / Weiss, Raul / Simonetti, Orlando P / Hummel, John D / Fedorov, Vadim V

URL

http://hdl.handle.net/2292/44203

Related subjects

Heart Atria / Humans / Atrial Fibrillation / Fibrosis / Magnetic Resonance Imaging / Catheter Ablation / Predictive Value of Tests / Action Potentials / Heart Rate / Models, Cardiovascular / Time Factors / Middle Aged / Female / Epicardial Mapping / Atrial Remodeling / Patient-Specific Modeling

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