Effects of Febuxostat in Early Gout: A Randomized, Double-Blind, Placebo-Controlled Study.

About this item

Title

Effects of Febuxostat in Early Gout: A Randomized, Double-Blind, Placebo-Controlled Study.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

To assess the effect of treatment with febuxostat versus placebo on joint damage in hyperuricemic subjects with early gout (1 or 2 gout flares).In this double-blind, placebo-controlled study, 314 subjects with hyperuricemia (serum uric acid [UA] level of ≥7.0 mg/dl) and early gout were randomized 1:1 to receive once-daily febuxostat 40 mg (increased to 80 mg if the serum UA level was ≥6.0 mg/dl on day 14) or placebo. The primary efficacy end point was the mean change from baseline to month 24...

Read more

Format

Research paper

Research format

Journal article

Date created

2017-12

Creator

Dalbeth, Nicola / Saag, Kenneth G / Palmer, William E / Choi, Hyon K / Hunt, Barbara / MacDonald, Patricia A / Thienel, Ulrich / Gunawardhana, Lhanoo

URL

http://hdl.handle.net/2292/44365

Related subjects

Joints / Humans / Gout / Synovitis / Hyperuricemia / Uric Acid / Gout Suppressants / Magnetic Resonance Imaging / Treatment Outcome / Double-Blind Method / Adult / Middle Aged / Female / Male / Febuxostat

What is the copyright status of this item?

Share, Modify

See below for specifics about how you may use this item.

More Information

The University of Auckland Library has this to say about the rights status of this item:

Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.

You can learn more about the rights status of this item at:

• https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm
• https://creativecommons.org/licenses/by-nc/4.0/
• http://purl.org/eprint/accessRights/OpenAccess

What can I do with this item?

You must always check with The University of Auckland Library to confirm the specific terms of use, but this is our understanding:

Non-infringing use

NZ Copyright law does not prevent every use of a copyright work. You should consider what you can and cannot do with a copyright work.

Share it

This item is suitable for copying and sharing with others, without further permission.

Modify it

This item is suitable for modifying, remixing and building upon, without further permission.

No commercial use

You may not use this item commercially.