Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents.

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Title

Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents.

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The University of Auckland Library

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ResearchSpace@Auckland

Description

Major depressive disorder (MDD) in children and adolescents is a recurrent and disabling condition globally but its pathophysiology remains poorly elucidated and there are limited effective treatments available. We performed metabolic profiling of plasma samples based on ultra-high-performance liquid chromatography equipped with quadrupole time-offlight mass spectrometry to explore the potential biomarkers of depression in children and adolescents with MDD. We identified several perturbed pat...

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Format

Research paper

Research format

Journal article

Date created

2019-10

Creator

Zhou, Xinyu / Liu, Lanxiang / Lan, Xinghui / Cohen, David / Zhang, Yuqing / Ravindran, Arun V / Yuan, Shuai / Zheng, Peng / Coghill, David / Yang, Lining / Hetrick, Sarah / Jiang, Xiaofeng / Benoliel, Jean-Jacques / Cipriani, Andrea / Xie, Peng

URL

http://hdl.handle.net/2292/44826

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