The lens internal microcirculation system delivers solutes to the lens core faster than would be predicted by passive diffusion.

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Title

The lens internal microcirculation system delivers solutes to the lens core faster than would be predicted by passive diffusion.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

It has been proposed that optical properties of the lens are actively maintained by an internal microcirculation system that utilizes ionic and fluid fluxes to deliver nutrients to deeper regions of the lens tissue via the extracellular space faster than would occur by passive diffusion alone. To test this hypothesis, we utilized a range of commercially available magnetic resonance imaging (MRI) reagents of varying molecular sizes that served as tracers of extracellular solute delivery. The p...

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Format

Research paper

Research format

Journal article

Date created

2018-11

Creator

Vaghefi Rezaei, Seyed / Donaldson, Paul

URL

http://hdl.handle.net/2292/45530

Related subjects

Microcirculation / Lens, Crystalline / Extracellular Space / Animals / Cattle / Cataract / Contrast Media / Magnetic Resonance Imaging / Diffusion

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