Structural and Biophysical studies of human Keratin-Associated Proteins and Peptidyl Arginine Deiminase III

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Title

Structural and Biophysical studies of human Keratin-Associated Proteins and Peptidyl Arginine Deiminase III

Content partner

The University of Auckland Library

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ResearchSpace@Auckland

Description

Keratin-associated proteins (KAPs) were identified 70 years ago in wool follicles. KAPs are encoded by several multi-gene families and are classified into three different groups: ultra-high sulphur (UHS), high sulphur (HS) and high glycine-tyrosine (HGT). KAPs are the major constituent of the matrix between the hair keratin intermediate filaments (IFs), and stabilise hair structure by extensive disulfide bonding. The expression and purification of KAPs is challenging because they are cysteine...

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Format

Research paper

Research format

Thesis

Thesis level

Doctoral

Date created

2018

Creator

Rechiche, Mohamed Othman

URL

http://hdl.handle.net/2292/37703

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